- 商品介绍
- 规格参数
- 包装参数
Application
BTZO-1 may be used in ARE-mediated gene expression studies.
Biochem/physiol Actions
BTZO-1 is a suppressor of cardiomyocyte apoptosis presumably by activation of antioxidant response element (ARE)-mediated gene expression. BTZO-1 binds to the macrophage migration inhibitory factor (MIF) that is required to activate the glutathione S-transferase Ya subunit (GST Ya) gene ARE.
suppressor of cardiomyocyte apoptosis; ligand of macrophage migration inhibitory factor (MIF)
Features and Benefits
This compound was developed by Takeda. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to tan |
| solubility | DMSO: ≥7 mg/mL |
| originator | Takeda |
| storage temp. | 2-8°C |
| SMILES string | O=C1N=C(Sc2ccccc12)c3ccccn3 |
| InChI | 1S/C13H8N2OS/c16-12-9-5-1-2-7-11(9)17-13(15-12)10-6-3-4-8-14-10/h1-8H |
| InChI key | GBAKVEWPYUIGHN-UHFFFAOYSA-N |
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