- 商品介绍
- 规格参数
- 包装参数
Immunogen
The epitope recognized by PLA0277 maps to a region between residue 726 and 776 of human Cullin 1 using the numbering given in entry NP_003583.2 (GeneID 8454).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
Cullin 1 (Cul1) is the core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, Cul1 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul1 may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13616]
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | human, mouse |
| technique(s) | immunoprecipitation (IP): 2-10 μg/mg,western blot: 1:2,000- 1:10,000 |
| accession no. | NP_003583.2 |
| UniProt accession no. | Q13616 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | rabbit ... Cul1(8454) |
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¥ 1683.78
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¥ 5887.85
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¥ 6330.00
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¥ 1653.62
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¥ 5061.38
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¥ 3404.94
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