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产品介绍
Product Description
Biochem/physiol Actions
Selective, high-affinity sigma-1 receptor antagonist with antinociceptive efficacy in vivo.
S1RA (E-52862) is a selective, high-affinity sigma-1 receptor antagonist (human/guinea pig σ1 Ki = 17/23.5 nM; σ2 Ki = 9.3 μM/rat, >1 μM/guinea pig). S1RA exerts dose-dependent antinociceptive effects in several neuropathic pain models in mice in vivo (16 - 64 mg/kg i.p.).
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | , White to light Brown |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | room temp |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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