α-Nicotinamide adenine dinucleotide,250MG,N6754-250MG,Sigma

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订货号 0BL3383
品牌型号 Sigma N6754-250MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Nicotinamide adenine dinucleotide (NAD) is an important cofactor for oxidation-reduction reactions in mitochondria.


Application

α-Nicotinamide adenine dinucleotide has been used in superoxide dismutase activity of seminal plasma samples and in glutathione peroxidase assay of liver, kidney, testes and brain samples.
α-Nicotinamide adenine dinucleotide (αNAD) may be used together with other NAD analogues to study the specificity and kinetics of NAD-dependent and NAD-transporting enzymes and proteins, such as NAD-glycohydrolase(s) and the mitochondrial NAD+ transporter in Saccharomyces cerevisiae.


Biochem/physiol Actions

α-Nicotinamide adenine dinucleotide (α-NAD) is a substrate for renalase. α-NAD, an analog of β-NAD, when used modulates kinetics of NAD dependent enzymes.


Other Notes

α analog of β-NAD


Disclaimer

This is not the common NAD required in the usual enzyme systems.


技术参数 Specifications
biological sourceSaccharomyces cerevisiae
Quality Level200
assay≥95%
formpowder
impurities≤1% β-isomer
solubilityH2O: soluble-50 mg/mL, clear, colorless to faintly yellow
storage temp.−20°C
SMILES stringNC(=O)c1ccc[n+](c1)[C@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O
InChI1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20+,21-/m1/s1
InChI keyBAWFJGJZGIEFAR-OPDHFMQKSA-N
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