- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
SKA-31 is an activator of KCa2 and KCa3.1 calcium-activated potassium channels.
SKA-31 is an activator of KCa2 and KCa3.1 calcium-activated potassium channels. Its EC50 is almost identical at 2-3 μM for all KCa2 subtypes, and about 10-fold lower (260 nM) at KCa3.1 channels. It has significant blood-pressure reducing activity in experimentally hypertensive mice, suggesting potassium channel activation as a therapeutic target for hypertension.
SKA31 is an activator of KCa2 and KCa3.1
SKA31 is an activator of KCa2 and KCa3.1 Potassium Channels, Potentiates the EDHF Response and Lowers Blood Pressure.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| solubility | DMSO: ≥30 mg/mL |
| storage temp. | −20°C |
| SMILES string | Nc1nc2c(ccc3ccccc23)s1 |
| InChI | 1S/C11H8N2S/c12-11-13-10-8-4-2-1-3-7(8)5-6-9(10)14-11/h1-6H,(H2,12,13) |
| InChI key | FECQXVPRUCCUIL-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 1259.40
-
询价
-
询价
-
询价
-
¥ 8135.09
-
询价
-
¥ 15214.65
-
¥ 4404.38
-
¥ 2268.97
-
¥ 3319.60
-
¥ 1509.00
-
¥ 745.60
-
¥ 5061.38
-
询价
-
¥ 165230.53
-
¥ 42661.77
-
¥ 15894.19
-
¥ 402833.12
-
询价
-
询价
微信小程序
7X24小时在线咨询