Biochem/physiol Actions
Hydroxyisoflavan isolated from Cuban and Brazilian red propolis that exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities.
(±)-Vestitol is a hydroxyisoflavan isolated from Cuban and Brazilian red propolis, licorice root and other sources that exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities. Apparently Vestitol inhibits release of the chemokines CXCL1/KC and CXCL2/MIP-2 from macrophages. Vestitol strongly inhibits Chikungunya virus infection. Vestitol exhibits anti-trypanosomal activity against T. brucei and T. congolense (EC50 3.86 and 4.36 µg/ml).