TCS OX2 29 HCl，25MG，SML2879-25MG，Sigma

Biochem/physiol Actions

A potent and selective orexin 2 receptor antagonist for studying Ox2R physiological functions both in cultures and in mice and rats in vivo.
TCS OX2 29 or TCS-OX2-29 is a potent and selective orexin 2 receptor (Ox2R, Ox2-R, Ox-2-R) antagonist (IC50 = 40 nM/Ox2R, >10 μM/Ox1R) with little potency toward 50 other receptors, ion channels, and transporters tested (<30% inhibition at 10 μM). TCS OX2 29 is widely used for elucidating various physiological functions mediated by Ox2R both in cultures and in mice and rats in vivo.