URB597,5MG,U4133-5MG,Sigma

销售价: ¥ 1335.35 / 件
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订货号 0BL6879
品牌型号 Sigma U4133-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

URB597 binds to active sites of fatty acid amide hydrolases and inhibits their activity. URB597 alters expression of tyrosine hydroxylase and interacts with abnormal-cannabidiol (Abn-CBD) and peroxisome proliferator-activated receptors (PPARs). URB597 elicits antinociception property via cannabinoid receptor by maintaining endocannabinoid anandamide (AEA) levels. URB597 reduces abnormal hyperactivity in neurons and could be for treatment of seizures and improving synaptic plasticity.


Biochem/physiol Actions

Potent, selective fatty acid amide hydrolase (FAAH) inhibitor.


Preparation Note

URB597 is soluble in DMSO at a concentration that is approximately 14 mg/ml.


技术参数 Specifications
descriptionDrug Control: Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet.
Quality Level100
assay≥98% (HPLC)
formpowder
drug controlÚj pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet
color white
solubilityDMSO: soluble ~14 mg/mL
storage temp.2-8°C
SMILES stringNC(=O)c1cccc(c1)-c2cccc(OC(=O)NC3CCCCC3)c2
InChI1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
InChI keyROFVXGGUISEHAM-UHFFFAOYSA-N
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