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Biochem/physiol Actions
Decursinol Angelate is a pyranocoumarin isolated from medical plant Angelica gigas that exhibits potent anti-inflammatory properties. Decursinol Angelate appears to suppress type 17 helper T (Th17) cell responses in dextran sodium sulfate-induced colitis model. Decursinol Angelate reduces the production of NF-κB and COX-2 induced proinflammatory cytokine levels on TPA induced mice ear edema.
Main anti-inflammatory component of Angelica gigas extract
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | [o]1c2c(cc3c(c2)OC([C@H](C3)OC(=O)\C(=C/C)\C)(C)C)cc[c]1=O |
| InChI | 1S/C19H20O5/c1-5-11(2)18(21)23-16-9-13-8-12-6-7-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/b11-5-/t16-/m0/s1 |
| InChI key | AGABNGOXUSXQDD-XKGFZTIGSA-N |
| 长度(mm) | |
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