Nelarabine，50MG，SML1736-50MG，Sigma

销售价： ¥ 4617.19 / 件

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订货号： 0BL7096

品牌型号： Sigma SML1736-50MG

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最小订货量： 1件

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商品介绍
规格参数
包装参数

产品介绍 Product Description

Biochem/physiol Actions

Antineoplastic purine nucleoside analog used in T-cell acute lymphoblastic leukemia; pro-drug of Ara-G.
Nelarabine is an antineoplastic purine nucleoside analog used in T-cell acute lymphoblastic leukemia. It is a pro-drug of Ara-G, which is converted by cellular kinases to the active 5′-triphosphate, Ara-GTP. Incorporation of Ara-GTP into DNA leads to inhibition of DNA synthesis and apoptosis.

技术参数 Specifications

Quality Level	100
assay	≥98% (HPLC)
form	powder
storage condition	desiccated
color	white to beige
solubility	H₂O: 5 mg/mL, clear (warmed)
storage temp.	2-8°C
SMILES string	O[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C=NC3=C2N=C(N)N=C3OC
InChI	1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10?/m1/s1
InChI key	IXOXBSCIXZEQEQ-KBNQYOMWSA-N