Mitoglitazone,5MG,SML1884-5MG,Sigma

销售价: ¥ 1041.61 / 件
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订货号 0BL8854
品牌型号 Sigma SML1884-5MG
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最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

MSDC-0160 is an mTOT (mitochondrial target of thiazolidinediones) modulator that targets the mitochondrial pyruvate carrier (MPC), which is a key controller of cellular metabolism. MSDC-0160 is reported to enhance the cells′ ability to handle potentially harmful proteins, which leads to reduced inflammation and less nerve cell death. It has already been in clinical trials for diabetes and Alzheimer′s disease and clinical trials for Parkinson′s Disease are planned.
Mitochondrial pyruvate carrier (MPC) inhibitor


技术参数 Specifications
Quality Level100
assay≥98% (HPLC)
formpowder
color white to beige
solubilityDMSO: 20 mg/mL, clear
storage temp.−20°C
SMILES stringCCC1=CN=C(C(COC2=CC=C(CC3SC(NC3=O)=O)C=C2)=O)C=C1
InChI1S/C19H18N2O4S/c1-2-12-5-8-15(20-10-12)16(22)11-25-14-6-3-13(4-7-14)9-17-18(23)21-19(24)26-17/h3-8,10,17H,2,9,11H2,1H3,(H,21,23,24)
InChI keyIRNJSRAGRIZIHD-UHFFFAOYSA-N
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