肝素钠猪粘膜,1EA,SRE0027-10MU,Sigma

销售价: ¥ 277073.50 / 件
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订货号 0BL9023
品牌型号 Sigma SRE0027-10MU
货期 询货期
最小订货量 1件
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  • 商品介绍
  • 规格参数
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产品介绍 Product Description

General description

Heparin is a polymer classified as a mucopolysaccharide or a glycosaminoglycan. It is biosynthesized and stored in mast cells of various mammalian tissues, particularly liver, lung, and mucosa. Commercial heparin is chiefly isolated from beef lung or pork intestinal mucosa.


Application

  • Heparin is traditionally used as an anticoagulant. It binds to antithrombin III, a naturally occurring plasma protease inhibitor, accelerating significantly the rate at which antithrombin III (AT-III) inhibits coagulation proteases (Factor Xa and thrombin).
  • In addition, heparin is shown to stabilize tryptase as an enzymatically active tetramer.


Features and Benefits

Features:

  1. Qualified Raw Materials: Products that meet the stringent requirements of the Elevated Assurance Program, ensuring compliance with regulatory standards.
  2. Comprehensive Documentation: Includes essential documents such as certificates, impurity profiles, and declarations to support audits and risk assessments.
  3. M-Clarity Quality Attributes: Products are classified within the MQ300 quality segment or higher, demonstrating superior quality assurance. M-Clarity Program
  4. Confirmed Process Controls: Established processes that ensure consistency and reliability in manufacturing.
  5. Enhanced Change Notification: Timely updates on any changes to product specifications or processes, ensuring transparency and compliance.
  6. Freely Available Dossiers: Access to robust, ready-to-present product dossiers that include:
    1. Site quality assessment
    2. ISO 9001 certificate
    3. Detailed product specifications
    4. Relevant declarations/statements (e.g., animal origin content, BSE/TSE, nitrosamine)
Benefits:
  1. Regulatory Compliance: Helps you meet compliance standards effectively, reducing the risk of regulatory issues.
  2. Audit Readiness: Instills confidence during audits with comprehensive documentation and confirmed process controls, demonstrating your commitment to high-quality products.
  3. Operational Transparency: Supports supply chain transparency, allowing you to track and verify the quality of raw materials.
  4. Enhanced Support: Provides exceptional quality-related information and tailored assistance to meet your specific needs.
  5. Risk Mitigation: Facilitates thorough risk assessments with detailed documentation, helping you manage potential compliance challenges.
  6. Informed Decision-Making: Access to clear and comprehensive product information enables better decision-making and enhances operational efficiency.


Other Notes

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。


Legal Information

M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany


技术参数 Specifications
biological sourcePorcine (mucosa)
Quality Level400
formpowder
color white to off-white
solubilitywater: 50 mg/mL (colorless to faint yellow)
application(s)diagnostic assay manufacturing
SMILES string[Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O
InChI1S/C26H42N2O37S5.Na/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36;/h5-20,23-26,28-29,31-
InChI keyJRTRSJGZMRQDHI-UHFFFAOYSA-N
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