- 商品介绍
- 规格参数
- 包装参数
Application
Cannabigerol may be used to study its binding properties to cannabinoid CB1 (CB1R) and CB2 (CB2R) receptors and its effects on agonist activation of those receptors and of CB1–CB2 heteroreceptor complexes.
Biochem/physiol Actions
Cannabigerol is a non-psychoactive phytocannabinoid. Cannabigerol binds CB1 and CB2 receptors with Ki values of 440 and 337 nM, respectively and acts as a partial agonist against CB1 and CB2 receptor subtypes. The compound is a potent a2-adrenoceptor agonist (EC50 = 0.2 nM). Cannabigerol modulates the expression of proinflammatory proteins, such as TNF-α, IL-1β, IL-6, IL-10, interferon-γ, and prostaglandin E2. CBG displays a broad spectrum of biological activities, including anti-inflammatory, antibacterial, and antifungal effects, as well as the regulation of redox balance and neuromodulatory properties.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | OC1=C(C(O)=CC(CCCCC)=C1)C/C=C(C)/CCC=C(C)C |
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