- 商品介绍
- 规格参数
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产品介绍
Product Description
Biochem/physiol Actions
BAY-899 is an orally available, potent and selective antagonist of the human luteinizing hormone receptor (hLH-R) that reduces sex hormone levels in several animal models. BAY-899 likely binds to a putative rhodopsin-like binding cavity located within the 7-transmembrane region of the hLH-receptor.
orally available, potent and selective antagonist of the human luteinizing hormone receptor (hLH-R)
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]/D 165 to 195°, c = 1 in chloroform-d |
| color | white to beige |
| solubility | DMSO: 1 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | O=C(N1[C@@H](C2=CC=C(F)C=C2)C3=C(N=CC=C3)CC1)NC4=CN=C(OC5=CC=C(F)C=C5)N=C4 |
| InChI | 1S/C25H19F2N5O2/c26-17-5-3-16(4-6-17)23-21-2-1-12-28-22(21)11-13-32(23)25(33)31-19-14-29-24(30-15-19)34-20-9-7-18(27)8-10-20/h1-10,12,14-15,23H,11,13H2,(H,31,33)/t23-/m0/s1 |
| InChI key | VKQBTIMLSDGNLG-QHCPKHFHSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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