- 商品介绍
- 规格参数
- 包装参数
Application
Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell. Investigation on the effect of Paris Saponin I (PS I) on human gastric carcinoma cell growth (SGC7901 cells) have shown an elevated level cytoplasmic cytochrome c. Results are an inhibition of proliferation in SGC7901 cells by inducing mitochondria-dependent apoptosis through cytochrome c.
Biochem/physiol Actions
The ready fluctuation of cytochrome c within the cell between ferrous and ferric states, makes it an efficient biological electron-transporter. It plays a vital role in cellular oxidations in both plants and animals. Generally regarded as a universal catalyst of respiration, it forms the essential electron-bridge between the respirable substrates and oxygen.
Preparation Note
Prepared with acetic acid without using TCA.
Other Notes
View more information on cytochrome c and electron transport at www.sigma-aldrich.com/enzymeexplorer.
| biological source | pigeon muscle (breast) |
| Quality Level | 200 |
| assay | ≥95% based on Mol. Wt. 12,173 basis |
| form | powder |
| technique(s) | cell culture | mammalian: suitable |
| storage temp. | −20°C |
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¥ 12156.68
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¥ 4164.19
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¥ 1653.62
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¥ 2842.54
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¥ 2617.87
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¥ 1476.00
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¥ 4020.77
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¥ 3476.87
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¥ 10685.48
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¥ 5804.96
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¥ 65710.50
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