- 商品介绍
- 规格参数
- 包装参数
Application
UCL 1684 ditrifluoroacetate hydrate has been used for analyzing the mechanism for ammonium-mediated displacement of the protonated analyte from analyte-trifluoroacetic acid (TFA) ion-pair. UCL 1684 has also been used as a potassium channel inhibitor to study CNP (C-type natriuretic peptide)-induced relaxations in pig coronary arteries.
Biochem/physiol Actions
UCL 1684 is a potent non-peptide blocker of the apamin-sensitive Ca2+-activated K+ channel. It comprises two quinolinium rings and is similar to apamin arginine residue. UCL 1684 inhibits calcium-activated K current (Kslow) and modulates islet β-cell.
Features and Benefits
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
UCL 1684 ditrifluoroacetate hydrate is soluble in water at 10 mg/ml.
| color | white to off-white |
| Quality Level | 100 |
| solubility | DMSO: 10 mg/mL |
| SMILES string | [H]O[H].FC(F)(C(O)=O)F.FC(F)(C(O)=O)F.C12=CC=CC=C1C(NCC3=CC=C(CNC4=CC=[N+](C5)C6=C4C=CC=C6)C=C3)=CC=[N+]2CC7=CC=CC5=C7 |
| InChI | 1S/C34H28N4.2C3H3F3O2.H2O/c1-3-10-33-29(8-1)31-16-18-37(33)23-27-6-5-7-28(20-27)24-38-19-17-32(30-9-2-4-11-34(30)38)36-22-26-14-12-25(13-15-26)21-35-31;2*4-3(5,6)1-2(7)8;/h1-20H,21-24H2;2*1H2,(H,7,8);1H2/b35-31+,36-32+;;; |
| InChI key | YROHEYZVNZITJN-DDVHGCDCSA-N |
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¥ 1302.89
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¥ 5887.85
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¥ 6330.00
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¥ 1476.00
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¥ 1509.00
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¥ 1196.14
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