醋酸去氧皮质酮,25G,D7000-25G,Sigma

销售价: ¥ 24503.72 / 件
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订货号 0BM3138
品牌型号 Sigma D7000-25G
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one.


Application

Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.


技术参数 Specifications
biological sourcesynthetic (organic)
Quality Level200
sterilitynon-sterile
assay≥98% (HPLC)
formpowder
solubilityH2O: insoluble,acetone: soluble (1 in 30),alcohol: soluble (1 in 50),chloroform: freely soluble,dioxane: slightly soluble,vegetable oils: slightly soluble
shipped inambient
storage temp.room temp
SMILES string[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@]([H])(CC[C@@]24[H])C(=O)COC(C)=O
InChI1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1
InChI keyVPGRYOFKCNULNK-ACXQXYJUSA-N
Gene Informationhuman ... NR3C2(4306)
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