- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
Nutlin-3b, a (+)-enantiomer of Nutlin-3, is a weakly potent antagonist of p53/MDM2 (IC50 = 13.6 μM) that can serve as negative control for Nutlin-3a (IC50 = 90 nM) and other Mdm2 inhibitors.
weakly potent antagonist of p53/MDM2 that can serve as negative control for Nutlin-3a
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | ClC(C=C1)=CC=C1[C@@H]2[C@H](C3=CC=C(Cl)C=C3)N(C(N4CCNC(C4)=O)=O)C(C5=C(OC(C)C)C=C(OC)C=C5)=N2 |
| InChI | 1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,16,18,27-28H,14-15,17H2,1-3H3,(H,33,37)/t27-,28+/m1/s1 |
| InChI key | BDUHCSBCVGXTJM-IZLXSDGUSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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