Monoclonal Anti-ACVR1C antibody produced in mouse,100UG,SAB1402660-100UG,Sigma

销售价: ¥ 5395.16 / 件
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订货号 0BM6208
品牌型号 Sigma SAB1402660-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM


Immunogen

ACVR1C (AAH22530.1, 23 a.a. ~ 112 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPM


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone2E3, monoclonal
formbuffered aqueous solution
mol wtantigen ~35.9 kDa
species reactivityhuman
technique(s)indirect ELISA: suitable,proximity ligation assay: suitable
isotypeIgG2aκ
NCBI accession no.BC022530
UniProt accession no.Q8NER5
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ACVR1C(130399)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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