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- 规格参数
- 包装参数
General description
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cofilin (P23528).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| material | colorless |
| clone | 4M1Z9, monoclonal |
| form | liquid |
| mol wt | 18 kDa |
| species reactivity | human, rat |
| concentration | 1.5 mg/mL |
| technique(s) | western blot: 1:500 - 1:2000 |
| color | colorless |
| isotype | IgG |
| immunogen sequence | MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLV |
| UniProt accession no. | P23528 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... Cofilin(1072) |
| 长度(mm) | |
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| 重量(kg) |
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¥ 12156.68
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¥ 4164.19
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¥ 2814.26
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¥ 4968.78
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¥ 5725.45
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¥ 3290.05
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¥ 2882.02
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¥ 2617.87
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¥ 1749.15
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¥ 4011.97
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¥ 8137.12
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