- 商品介绍
- 规格参数
- 包装参数
Application
Eupatilin has been used to investigate its inhibitory effects on intracranial hemorrhage (ICH)-induced inflammation and its anti-inflammatory mechanisms in mouse BV2 cells, in vitro. It has also been used as a standard for its quantitative estimation in Artemisia extracts by microcolumn high performance liquid chromatography with diode array (HPLC-DAD) assay.
Biochem/physiol Actions
Eupatilin is an important constituent in the leaves of Artemisia argyi and also an active component of DA-9601. It exhibits anti-apoptotic effects. Eupatilin provides protection against tumor necrosis factor α (TNF-α)-mediated inflammation in human umbilical vein endothelial cells. It is used in the treatment of gastritis and peptic ulcers. Eupatilin safeguards gastric epithelial cells from oxidative damage and smooth muscle cells from indomethacin-induced cell damage. Eupatilin lowers bile acid-stimulated hepatocyte apoptosis.
Eupatilin is a flavone with anti-oxidative, anti-inflammatory, and anti-cancer properties.
Flavone with anti-oxidative, anti-inflammatory, and anti-cancer properties
| biological source | (Isolated from Artemisia sp.) |
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated,protect from light |
| color | white to beige |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=C(OC)C(O)=C31 |
| InChI | 1S/C18H16O7/c1-22-12-5-4-9(6-14(12)23-2)13-7-10(19)16-15(25-13)8-11(20)18(24-3)17(16)21/h4-8,20-21H,1-3H3 |
| InChI key | DRRWBCNQOKKKOL-UHFFFAOYSA-N |
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¥ 2814.26
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¥ 2013.69
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¥ 5725.45
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¥ 10277.12
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¥ 1196.14
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¥ 2406.69
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¥ 954.17
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¥ 2888.88
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¥ 70526.15
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¥ 145427.01
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¥ 14985.93
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