- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
VU0409551 (JNJ-46778212) is an orally available, potent and selective biased metabotropic glutamate receptor subtype 5 positive allosteric modulator (mGlu5 PAM). VU0409551 (JNJ-46778212) selectively potentiates mGlu5 coupling to Gaq-mediated signaling without modulation of NMDAR currents in hippocampal neurons. VU0409551 exhibits potent antipsychotic-like and cognition enhancing activity in animal models.
orally available, potent and selective biased mGlu5 PAM
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | O=C(N1CCC2=C(C1)OC(COC3=CC=CC=C3)=N2)C4=CC=C(C=C4)F |
| InChI key | QUZLMKNNIUSREV-UHFFFAOYSA-N |
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¥ 1148.92
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¥ 2814.26
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¥ 1563.36
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¥ 1956.41
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmSFCA滤膜，孔径0.2um,适合瓶颈尺寸45mm，12/箱，291-4520，Nalgene，Thermofisher，赛默飞世尔¥ 2856.42
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¥ 2307.00
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¥ 1564.00
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¥ 1196.00
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¥ 5014.59
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¥ 2869.87
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¥ 2406.69
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