- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
INDY is a potent inhibitor of Dyrk1A and Dyrk1B (dual-specificity tyrosine-phosphorylation-regulated kinase 1). The IC50 values for inhibition of Dyrk1A and 1B are 240 and 230 nM, respectively. INDY impairs the self-renewal capacity of neural stem cells and glioblastoma tumor-initiating cells.
INDY is a potent inhibitor of Dyrk1A and Dyrk1B.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage temp. | −20°C |
| SMILES string | S1c2c(cc(cc2)O)N(\C\1=C/C(=O)C)CC |
| InChI | 1S/C12H13NO2S/c1-3-13-10-7-9(15)4-5-11(10)16-12(13)6-8(2)14/h4-7,15H,3H2,1-2H3/b12-6+ |
| InChI key | GCSZJMUFYOAHFY-WUXMJOGZSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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