Atorvastatin calcium salt trihydrate,50MG,SML3030-50MG,Sigma

销售价: ¥ 3635.12 / 件
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订货号 0BN2454
品牌型号 Sigma SML3030-50MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

β-Hydroxy β-methylglutaryl-CoA (HMG-CoA) reductase inhibitor.
Atorvastatin calcium salt trihydrate is a specific inhibitor of β-Hydroxy β-methylglutaryl-CoA (HMG-CoA) reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia.


技术参数 Specifications
Quality Level100
assay≥98% (HPLC)
formpowder
optical activity[α]/D -9.0 to -5.0°, c = 0.5 in DMSO
storage conditionprotect from light
color white to beige
solubilityDMSO: 2 mg/mL, clear
storage temp.room temp
SMILES stringO=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C2=CC=C(C=C2)F)=C1C3=CC=CC=C3)NC4=CC=CC=C4.[Ca+2].[3.0H2O]
InChI1S/2C33H35FN2O5.Ca.3H2O/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;;;;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);;3*1H2/q;;+2;;;/p-2/t2*26-,27-;;;;/m11..../s1
InChI keySHZPNDRIDUBNMH-NIJVSVLQSA-L
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