Succinobucol,25MG,SML2182-25MG,Sigma

销售价: ¥ 1299.57 / 件
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订货号 0BN3038
品牌型号 Sigma SML2182-25MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

Orally active antioxidant; vascular protectant; antiatherosclerotic;
Succinobucol is a metabolically stable derivative of the antioxidant drug probucol that poses a distinct pharmacological from. Succinobucol is an orally active vascular protectant that exhibits antiatherosclerotic properties in multiple animal models and in humans. It inhibits the release of proinflammatory cytokines, TNF-a, IL-1b, and IL-6 in hPBMC activated by LPS.


技术参数 Specifications
assay≥98% (HPLC)
formpowder
color white to beige
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
SMILES stringOC1=C(C(C)(C)C)C=C(SC(C)(C)SC2=CC(C(C)(C)C)=C(OC(CCC(O)=O)=O)C(C(C)(C)C)=C2)C=C1C(C)(C)C
InChI1S/C35H52O5S2/c1-31(2,3)23-17-21(18-24(29(23)39)32(4,5)6)41-35(13,14)42-22-19-25(33(7,8)9)30(26(20-22)34(10,11)12)40-28(38)16-15-27(36)37/h17-20,39H,15-16H2,1-14H3,(H,36,37)
InChI keyRKSMVPNZHBRNNS-UHFFFAOYSA-N
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