- 商品介绍
- 规格参数
- 包装参数
General description
Histone H3.1 is a histone H3 variant. It differs from H3.2 with residue 96 being a cysteine instead of serine. H3.1 is a replication-dependent histone and is a component of nucleosomes during the S-phase.
Application
Histone H3.1 human has been used in in vitro Schizosaccharomyces pombe Set7 histone methyltransferase assay for matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF) studies.
Biochem/physiol Actions
Histone H3.1 human (H3.1) undergoes a majority of post-translational modification especially acetylation and demethylation in lysine 14 and 9 respectively. During differentiation, the levels of H3.1 transcripts decrease as cell division slows down. The incorporation of H3.1 into chromatin is mediated by a chaperone, chromatin assembly factor (CAF-1). A transversion mutation in the H3.1 may be implicated in glioma.
Physical form
Supplied as 1 mg/mL in 20 mM NaPO4, pH 7.0, 0.3 M NaCl, 1 mM EDTA, and 1 mM DTT.
| biological source | human |
| Quality Level | 200 |
| recombinant | expressed in E. coli |
| form | liquid |
| concentration | 1 mg/mL |
| technique(s) | MALDI-TOF: suitable |
| UniProt accession no. | P68431 |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... H3C1(8350) |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |





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