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Biochem/physiol Actions
TR100 is a specific anti-tropomyosin agent that preferentially disrupts the actin cytoskeleton of tumor cells.
TR100 is a specific anti-tropomyosin agent that preferentially disrupts the actin cytoskeleton of tumor cells. TR100 selectively disrupts Tm5NM1/2 containing actin filaments. TR100 induces apoptosis in a panel of neural crest-derived tumor cell lines with no adverse effects on cardiac structure and function.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| SMILES string | CC1=C(/C=C(C#N)\C(NCCCCCCCC)=O)C2=C(N1CCCN(C)C)C=CC=C2 |
| InChI | 1S/C26H38N4O/c1-5-6-7-8-9-12-16-28-26(31)22(20-27)19-24-21(2)30(18-13-17-29(3)4)25-15-11-10-14-23(24)25/h10-11,14-15,19H,5-9,12-13,16-18H2,1-4H3,(H,28,31)/b22-19- |
| InChI key | XXRLIGWROLDOLS-QOCHGBHMSA-N |
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