- 商品介绍
- 规格参数
- 包装参数
General description
Empagliflozin is a C-glucoside with a carbon-carbon bond between the glucose and aglycone, resisting the breakdown in the gastrointestinal tract.
Application
Empagliflozin may be used to study its effects on diabetes mellitus in animal models.
Biochem/physiol Actions
Empagliflozin (BI 10773) is an orally active, potent and highly selective sodium glucose co-transporter-2 inhibitor (hSGLT-2 IC50 = 3.1 nM; hSGLT-1/4/5/6 IC50 = 8.3/11/1.1/2.0 µM) that targets SGLT-2 with high affinity in a glucose-competitive manner (hSGLT-2 Kd = 57/194 nM in the absence/presence of 20 mM glucose). Empagliflozin improves glycaemic control in type 2 (1-3 mg/kg via daily p.o. to Zucker diabetic fatty (ZDF) rats) and type 1 (10 mg/kg b.i.d. p.o. to streptozotocin-induced diabetic (STD) rats) diabetes mellitus models.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| 长度(mm) | |
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| 重量(kg) |
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¥ 1683.78
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¥ 4173.75
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¥ 1724.25
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¥ 6330.00
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无菌，PETG 方形有刻度培养基瓶，带盖，聚对苯二酸乙二醇酯共聚物，天然高密度聚乙烯盖，500毫升容量，每箱40，40/箱，342020-0500，Nalgene，Thermofisher，赛默飞世尔¥ 3684.34
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¥ 5014.59
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¥ 2452.91
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NALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/8 x 1/4 x 1/16，英寸，每箱数量50，50/箱，8000-0020，Thermofisher，赛默飞世尔询价
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NNALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/4 x 1/2 x 1/8，英寸，每箱数量50，50/箱，8000-0080，Thermofisher，赛默飞世尔
询价
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¥ 70526.15
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