Monoclonal Anti-ERCC2 antibody produced in mouse,100UG,SAB1408981-100UG,Sigma

销售价: ¥ 4585.89 / 件
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订货号 0BN6642
品牌型号 Sigma SAB1408981-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)


Immunogen

ERCC2 (NP_000391, 631 a.a. ~ 730 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
RILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHR


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone2C9, monoclonal
formbuffered aqueous solution
mol wtantigen 36.74 kDa
species reactivityhuman
technique(s)immunofluorescence: suitable,indirect ELISA: suitable
isotypeIgG2bκ
NCBI accession no.NM_000400
UniProt accession no.P18074
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ERCC2(2068)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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