Cromakalim，50MG，C1055-50MG，Sigma

Application

Cromakalim has been used:

• as a potassium channel agonist to study its response to an acute increase in downstream pressure in rat lymphatic vessels.
• as a potassium channel opener to study its effects on the release of transmitters from adrenergic nerves in rat vas deferens.
• as a potassium channel activator to study its effects on the release of transmitters from purinergic and cholinergic nerves in the rat detrusor muscle.

Biochem/physiol Actions

Cromakalim is an activator of the potassium channel. It is involved in the relaxation of the vascular smooth muscles. Cromakalim exhibits anti-hypertensive activity.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.