- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
General description
Fumagillin is a metabolic product of fungi. It is originally isolated from Aspergillus fumigatus.
Application
Fumagillin from Aspergillus fumigatus has been used:
- in chick chorioallantoic membrane (CAM) assay to study the changes in protein expression in response to anti-angiogenic agent
- to study its effects on the mortality of caged Nosema ceranae-infected honey bees- write in this way
- as a positive control in in vitro and ex vivo studies
Biochem/physiol Actions
Fumagillin is known to be effective against microsporidian fungal infections.
Methionine aminopeptidase-2 (MetAP-2) inhibitor; inhibits endothelial cell proliferation and angiogenesis.
技术参数
Specifications
| biological source | Aspergillus sp. (Aspergillus fumigatus) |
| Quality Level | 200 |
| assay | ≥90% |
| form | powder |
| color | white |
| mp | 197-198 °C |
| solubility | ethanol: 1 mg/mL |
| antibiotic activity spectrum | fungi |
| mode of action | DNA synthesis | interferes |
| storage temp. | −20°C |
| SMILES string | COC1C(CCC2(CO2)C1C3(C)OC3C\C=C(\C)C)OC(=O)\C=C\C=C\C=C\C=C\C(O)=O |
| InChI | 1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+ |
| InChI key | NGGMYCMLYOUNGM-HCNIIHBUSA-N |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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