Rostafuroxin,5MG,SML1139-5MG,Sigma

销售价: ¥ 1496.10 / 件
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订货号 0BP8260
品牌型号 Sigma SML1139-5MG
货期 询货期
最小订货量 1件
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实验室两箱一柜(超低温冰箱、培养箱、生物安全柜)、离心机
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产品介绍 Product Description

Biochem/physiol Actions

Rostafuroxin is a Na-K ATPase; Ouabain antagonist.
Rostafuroxin is a derivative of digitoxigenin. It protects animal models against podocyte lesions and proteinuria by counteracting mutant β-adducin and ouabain-mediated effects.
Rostafuroxin is a digitoxygenin derivative that selectively antagonizes the effects of endogenous ouabain on the Na+,K+-ATPase, which maintains sodium and potassium ion gradients across plasma membranes. Rostafuroxin lowers blood pressure (BP) in animal models of hypertension.


技术参数 Specifications
Quality Segment100
assay≥98% (HPLC)
formpowder
color white to beige
solubilityDMSO: 20 mg/mL, clear
storage temp.−20°C
SMILES string[o]1cc(cc1)[C@@]2([C@@]3([C@@]([C@H]4[C@@H]([C@@]5([C@@H](C[C@H](CC5)O)CC4)C)CC3)(CC2)O)C)O
InChI1S/C23H34O4/c1-20-8-5-17(24)13-15(20)3-4-19-18(20)6-9-21(2)22(25,10-11-23(19,21)26)16-7-12-27-14-16/h7,12,14-15,17-19,24-26H,3-6,8-11,13H2,1-2H3/t15-,17+,18+,19-,20+,21-,22+,23+/m1/s1
InChI keyAEAPORIZZWBIEX-DTBDINHYSA-N
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