- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
E7820 (NSC 719239) is an orally available anticancer and antiangiogenic agent that inhibits VEGF-2 or FGF-2-induced tube formation of HUVEC cells through the suppression of integrin α2. E7820 promotes selective proteasomal degradation of the U2AF-related splicing factor CAPERα (coactivator of activating protein-1 and estrogen receptors) by ubiquitination and degradation via CRL4DCAF15.
inducer of selective proteasomal degradation of CAPERα
| ligand | E7820 |
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| reaction suitability | reagent type: ligand |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | [S](=O)(=O)(Nc2c3[nH]cc(c3c(cc2)C)C#N)c1cc(ccc1)C#N |
| InChI | 1S/C17H12N4O2S/c1-11-5-6-15(17-16(11)13(9-19)10-20-17)21-24(22,23)14-4-2-3-12(7-14)8-18/h2-7,10,20-21H,1H3 |
| InChI key | LWGUASZLXHYWIV-UHFFFAOYSA-N |
| 长度(mm) | |
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¥ 1302.89
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¥ 1779.22
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¥ 3275.78
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¥ 4897.21
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¥ 15214.65
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无菌，PETG 方形有刻度培养基瓶，带盖，聚对苯二酸乙二醇酯共聚物，天然高密度聚乙烯盖，500毫升容量，每箱40，40/箱，342020-0500，Nalgene，Thermofisher，赛默飞世尔¥ 3684.34
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¥ 3319.60
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¥ 2307.00
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¥ 1509.00
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¥ 1749.15
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¥ 2869.87
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¥ 5804.96
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