Biochem/physiol Actions
Prodrug form of paliperidone, is a long-acting injectable antipsychotic that targets dopamine and serotonin receptors.
Paliperidone palmitate is a long-acting injectable form of paliperidone, an atypical antipsychotic that targets dopamine D2 and serotonin 5-HT2A receptors to alleviate schizophrenia symptoms through neurotransmission regulation. Paliperidone palmitate also interacts with α1/α2 adrenergic and H1 histaminergic receptors, influencing both its therapeutic effects and side effect profile. The formulation′s sustained release mechanism promotes gradual absorption, ensuring stable drug levels for prolonged efficacy.