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Biochem/physiol Actions
Brain blood barrier penetrant ATP-sensitive potassium channel (KATP) opener that attenuates hypoxia-induced pulmonary arterial hypertension in rats; K(ir) 6.1/SUR2B activator.
Iptakalim hydrochloride is a brain blood barrier penetrant ATP-sensitive potassium channel (KATP) opener that attenuates hypoxia-induced pulmonary arterial hypertension in rats. Iptakalim hydrochloride is a selective antagonist of α4β2-containing nicotinic acetylcholine receptor (nAChR).
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Hygroscopic
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | H2O: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | [Cl-].[N+H2](C(C(C)C)(C)C)C(C)C |
| InChI | 1S/C9H21N.ClH/c1-7(2)9(5,6)10-8(3)4;/h7-8,10H,1-6H3;1H |
| InChI key | RXNJQAYLNOXYKW-UHFFFAOYSA-N |
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| 重量(kg) |
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