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Biochem/physiol Actions
Cell-permeable covalent ligand that selectively modifies a non-catalytic, allosteric cysteine C23 in the K48 ubiquitin-specific deubiquitinase OTUB1
EN523 is a cell-permeable covalent ligand that selectively modifies a non-catalytic, allosteric cysteine C23 in the K48 ubiquitin-specific deubiquitinase OTUB1. EN523 does not inhibit OTUB1 deubiquitination activity and serves as OTUB1 recruiter.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | O=C1N(CCN(C1)C(C=C)=O)C2=CC=C(O2)C |
| InChI | 1S/C12H14N2O3/c1-3-10(15)13-6-7-14(11(16)8-13)12-5-4-9(2)17-12/h3-5H,1,6-8H2,2H3 |
| InChI key | KYXPDOMFYBFXKO-UHFFFAOYSA-N |
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¥ 1779.22
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¥ 1866.29
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¥ 4039.86
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¥ 2617.87
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¥ 1749.15
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¥ 3662.39
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¥ 44224.19
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¥ 29754.56
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¥ 26846.31
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¥ 58855.47
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¥ 65710.50
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¥ 39676.71
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¥ 99441.38
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