- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
NCX 4040 is a nitric oxide-donating form of aspirin.
NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines.
Features and Benefits
This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | protect from light |
| color | white to beige |
| solubility | DMSO: 15 mg/mL (clear solution) |
| storage temp. | −20°C |
| SMILES string | CC(=O)Oc1ccccc1C(=O)Oc2ccc(CO[N+]([O-])=O)cc2 |
| InChI | 1S/C16H13NO7/c1-11(18)23-15-5-3-2-4-14(15)16(19)24-13-8-6-12(7-9-13)10-22-17(20)21/h2-9H,10H2,1H3 |
| InChI key | CTHNKWFUDCMLIQ-UHFFFAOYSA-N |
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¥ 9207.92
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¥ 4039.86
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¥ 5725.45
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