- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Tariquidar is a non-competitive inhibitor. It is used as a potential agent for checking the role of P-glycoprotein inhibition in cancer. Tariquidar also has an ability to enhance drug exposure in drug-resistant cancers.
Specific inhibitor of MDR-1 (P-gp)
Tariquidar is a potent MDR1 (P-gp, P-glycoprotein) inhibitor. Tariquidar reverses multidrug resistance (MDR) by inhibiting MDR1-mediated drug efflux.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to light brown |
| solubility | DMSO: 10 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | O=C(C1=CC(OC)=C(OC)C=C1NC(C2=CC(C=CC=C3)=C3N=C2)=O)NC(C=C4)=CC=C4CCN5CC6=CC(OC)=C(OC)C=C6CC5 |
| InChI | 1S/C38H38N4O6/c1-45-33-18-25-14-16-42(23-28(25)19-34(33)46-2)15-13-24-9-11-29(12-10-24)40-38(44)30-20-35(47-3)36(48-4)21-32(30)41-37(43)27-17-26-7-5-6-8-31(26)39-22-27/h5-12,17-22H,13-16,23H2,1-4H3,(H,40,44)(H,41,43) |
| InChI key | LGGHDPFKSSRQNS-UHFFFAOYSA-N |
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