- 商品介绍
- 规格参数
- 包装参数
General description
This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq, Sep 2016]
Immunogen
A synthesized peptide derived from human DROSHA.
Physical form
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody product type | primary antibodies |
| clone | monoclonal |
| form | liquid |
| species reactivity | human, mouse, rat |
| concentration | 1 mg/mL |
| technique(s) | immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000 |
| UniProt accession no. | Q9NRR4 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... DROSHA(29102) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |




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