Anti-DROSHA antibody produced in rabbit,100UL,SAB5701292-100UL,Sigma

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订货号 0BR0205
品牌型号 Sigma SAB5701292-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq, Sep 2016]


Immunogen

A synthesized peptide derived from human DROSHA.


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivityhuman, mouse, rat
concentration1 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.Q9NRR4
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... DROSHA(29102)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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