- 商品介绍
- 规格参数
- 包装参数
Application
Urocortin human can be used as a test compound for studying the impact of corticotropin-releasing factor (CRF) receptor agonist and antagonist on sleep-wake patterns in conscious rats by using radiotelemetry system.
Biochem/physiol Actions
Binds to CRF receptor types 1, 2α, and 2β.
Binds to CRF receptor types 1, 2α, and 2β; stimulates cAMP accumulation from cells transfected with these receptors. Acts in vitro to release ACTH from rat anterior pituitary cells.
Urocortin is a CRF-related neuropeptide having high affinity for CRF2 receptor possess appetite-suppressing effect. Urocortin along with corticotropin-releasing factor (CRF) binding protein (CRF-BP) enhances the free CRF levels in human brain by displacing hCRF from the binding protein.
| biological source | human |
| Quality Segment | 200 |
| assay | ≥85% (HPLC) |
| form | powder |
| technique(s) | ligand binding assay: suitable |
| UniProt accession no. | P55089 |
| storage temp. | −20°C |
| Gene Information | human ... UCN(7349) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 2622.09
-
¥ 1259.40
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 5725.45
-
询价
-
¥ 2869.87
-
¥ 3796.67
-
¥ 56581.65
-
¥ 165230.53
-
¥ 55311.07
-
¥ 30616.15
-
询价
-
¥ 108621.02
-
询价
-
询价
微信小程序
7X24小时在线咨询