- 商品介绍
- 规格参数
- 包装参数
Application
LY255582 may be used in opioid receptor-mediated cell signaling studies.
Biochem/physiol Actions
LY255582 inhibits the diet-associated increases in mesolimbic dopamine levels and reduces the consumption of highly-palatable food intake.
LY255582 is a centrally active opioid receptor antagonist
LY255582 is a centrally active opioid receptor antagonist (defined as an inverse agonist in 2011 JPET paper) that inhibited weight gain in obese Zucker rats over 30 days. It is more that 5-fold selective for mu opioid receptor compared to kappa opioid receptors and 13-fold selective over delta opioid receptors.
Features and Benefits
This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | DMSO: ≥15 mg/mL |
| originator | Eli Lilly |
| storage temp. | 2-8°C |
| SMILES string | C[C@H]1CN(CC[C@H](O)C2CCCCC2)CC[C@@]1(C)c3cccc(O)c3 |
| InChI | 1S/C22H35NO2/c1-17-16-23(13-11-21(25)18-7-4-3-5-8-18)14-12-22(17,2)19-9-6-10-20(24)15-19/h6,9-10,15,17-18,21,24-25H,3-5,7-8,11-14,16H2,1-2H3/t17-,21-,22+/m0/s1 |
| InChI key | LVVHEFJXPXAUDD-BULFRSBZSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 1573.49
-
¥ 9207.92
-
¥ 3109.49
-
询价
-
询价
-
询价
-
¥ 8135.09
-
询价
-
¥ 4968.78
-
询价
-
¥ 4390.38
-
询价
-
询价
-
询价
-
询价
-
¥ 1196.14
-
¥ 5061.38
-
¥ 3404.94
-
¥ 2911.61
-
NALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/8 x 1/4 x 1/16，英寸，每箱数量50，50/箱，8000-0020，Thermofisher，赛默飞世尔
询价
微信小程序
7X24小时在线咨询