Idazoxan hydrochloride,100MG,I6138-100MG,Sigma

销售价: ¥ 1557.91 / 件
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订货号 0BR4649
品牌型号 Sigma I6138-100MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Application

Idazoxan hydrochloride has been used to study the efficacy of antidepressant treatments that interact with multiple neurotransmitter systems.


Biochem/physiol Actions

α2-adrenoceptor antagonist; I2 imidazoline receptor agonist; I1 imidazoline receptor antagonist. Idazoxan can antagonize various behaviors generated by ethanol in a preclinical setting. It possesses neuroprotective activity against spinal cord injury, resulted due to experimental autoimmune encephalomyelitis (EAE) in mouse, an animal modal of multiple sclerosis (MS).


技术参数 Specifications
Quality Segment100
solubilityH2O: 50 mg/mL
SMILES stringCl.C1CN=C(N1)C2COc3ccccc3O2
InChI1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4,10H,5-7H2,(H,12,13);1H
InChI keyMYUBYOVCLMEAOH-UHFFFAOYSA-N
Gene Informationhuman ... ADRA2A(150), ADRA2B(151), ADRA2C(152)
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