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General description
FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ′fused toes′ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
Physical form
Solution in 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl.
Other Notes
Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.
| biological source | mouse |
| recombinant | expressed in E. coli |
| tag | His tagged |
| assay | >90% (SDS-PAGE) |
| form | liquid |
| mol wt | ~55 kDa by SDS-PAGE |
| packaging | pkg of 10 μg |
| storage condition | avoid repeated freeze/thaw cycles |
| concentration | ≥0.2 mg/mL |
| impurities | <1 EU/μg endotoxin, tested |
| color | clear |
| UniProt accession no. | Q8BGW1 |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | mouse ... Fto(26383) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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