Anti-MRPL43 antibody produced in mouse,50UG,SAB1408111-50UG,Sigma

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订货号 0BR7712
品牌型号 Sigma SAB1408111-50UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms. (provided by RefSeq)


Immunogen

MRPL43 (NP_115488.2, 1 a.a. ~ 159 a.a) full-length human protein.

Sequence
MTARGTPSRFLASVLHNGLGRYVQQLQRLSFSVSRDGASSRGAREFVEREVIDFARRNPGVVIYVNSRPCCVPRVVAEYLNGAVREESIHCKSVEEISTLVQKLADQSGLDVIRIRKPFHTDNPSIQGQWHPFTNKPTTFRGLRPREVQDPAPAQVQAQ


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wtantigen ~17.9 kDa
species reactivityhuman
technique(s)western blot: 1 μg/mL
NCBI accession no.NM_032112
UniProt accession no.Q8N983
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... MRPL43(84545)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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