- 商品介绍
- 规格参数
- 包装参数
Application
Tetrabenazine has been used for dopamine uptake assays in mouse brain cells1. Tetrabenazine has also been used for non-specific binding assays in postnuclear supernatants derived from PC-12 and CV-1 cells2.
Biochem/physiol Actions
Tetrabenazine is a reversible type 2 vesicular monoamine transporter (VMAT) inhibitor.
Tetrabenazine is a reversible type 2 vesicular monoamine transporter (VMAT) inhibitor. It depletes dopamine stores.
Features and Benefits
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Preparation Note
Tetrabenazine is soluble in DMSO at a concentration that is greater than 10 mg/ml and is insoluble in water.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| solubility | DMSO: >10 mg/mL,H2O: insoluble |
| originator | Roche |
| storage temp. | 2-8°C |
| SMILES string | COc1cc2CCN3C[C@@H](CC(C)C)C(=O)CC3c2cc1OC |
| InChI | 1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/m1/s1 |
| InChI key | MKJIEFSOBYUXJB-GDBMZVCRSA-N |
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