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Biochem/physiol Actions
6-Aminophenanthridine selectively inhibits protein folding activity of the ribosome (PFAR).
6-Aminophenanthridine selectively inhibits protein folding activity of the ribosome (PFAR). Apparently 6-Aminophenanthridine interacts with the ribosome domain V rRNA and the protein substrate. 6-Aminophenanthridine is an antiprion compound that promotes mammalian prion clearance.
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| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to brown |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | Nc1nc2c(c3c1cccc3)cccc2 |
| InChI | 1S/C13H10N2/c14-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)15-13/h1-8H,(H2,14,15) |
| InChI key | FVCXJXKLDUJOFA-UHFFFAOYSA-N |
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