Monoclonal Anti-PHOX2A antibody produced in mouse,100UG,WH0000401M1-100UG,Sigma

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订货号 0BS3233
品牌型号 Sigma WH0000401M1-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. (provided by RefSeq)


Immunogen

PHOX2A (NP_005160, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQ


Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.


Physical form

Solution in phosphate buffered saline, pH 7.4


Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone4F6, monoclonal
formbuffered aqueous solution
species reactivityrat, mouse, human
technique(s)indirect ELISA: suitable,indirect immunofluorescence: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
GenBank accession no.NM_005169
UniProt accession no.O14813
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... PHOX2A(401)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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