GSK046，5MG，SML3147-5MG，Sigma

销售价： ¥ 1428.61 / 件

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订货号： 0BS5007

品牌型号： Sigma SML3147-5MG

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最小订货量： 1件

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商品介绍
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包装参数

产品介绍 Product Description

General description

GSK046 is an orally bioavailable small molecule. Its structure contains a poly-substituted phenyl ring in the center. GSK046 reduces immuno-inflammation by inhibiting the production of monocyte chemoattractant protein 1 (MCP-1), a chemokine involved in the regulation of macrophage activation.

Biochem/physiol Actions

potent and highly selective inhibitor of bromodomain BD2 of BRD2, BDR3, BRD4, BRDT

技术参数 Specifications

Quality Segment	100
assay	≥98% (HPLC)
form	powder
color	white to beige
storage temp.	2-8°C
SMILES string	O=C(N[C@H]1CC[C@H](O)CC1)C2=CC(F)=C(NC(C)=O)C(O[C@H](C3=CC=CC=C3)C)=C2
InChI	1S/C23H27FN2O4/c1-14(16-6-4-3-5-7-16)30-21-13-17(12-20(24)22(21)25-15(2)27)23(29)26-18-8-10-19(28)11-9-18/h3-7,12-14,18-19,28H,8-11H2,1-2H3,(H,25,27)(H,26,29)/t14-,18-,19-/m0/s1
InChI key	FRBRZGLUFOZRGD-JVPBZIDWSA-N

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