群多普利,50MG,T4827-50MG,Sigma

销售价: ¥ 7332.07 / 件
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订货号 0BS7056
品牌型号 Sigma T4827-50MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Application

Trandolapril has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on responsiveness of human retinal endothelial cells (HRECs) to vascular endothelial growth factor (VEGF).


Biochem/physiol Actions

Studies have reported that trandolapril inhibits atherosclerosis1 and decreases the occurrence of atrial fibrillation2.
Trandolapril is an ACE inhibitor.
Trandolapril is an ACE inhibitor. Trandolapril differs from other ACE inhibitors in that it has a longer biological half-life and a high degree of lipophilicity.


Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


Preparation Note

Trandolapril is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml.


技术参数 Specifications
Quality Segment100
assay≥98% (HPLC)
formpowder
color white
solubilityDMSO: ≥20 mg/mL
originatorAbbott
SMILES stringCCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2C3CCCCC3C[C@H]2C(O)=O
InChI1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1
InChI keyVXFJYXUZANRPDJ-WTNASJBWSA-N
Gene Informationhuman ... ACE(1636)
长度(mm)
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