KAT8 (2-467), GST tagged human,20UG,SRP5220-20UG,Sigma

销售价: ¥ 2687.32 / 件
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订货号 0BS7060
品牌型号 Sigma SRP5220-20UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Lysine acetyltransferase 8 (KAT8) or MYST histone acetyltransferase 1 (MYST1) is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs). MYST1 has a chromodomain that is involved in protein-protein interactions and targeting transcriptional regulators to the chromatin.


Biochem/physiol Actions

Lysine acetyltransferase 8 (KAT8) or MYST histone acetyltransferase 1 (MYST1) was originally isolated as a human immunodeficiency virus-1 (HIV-1) TAT-interactive protein, which plays important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and non-histone proteins. MYST1 is also involved in ataxia-telangiectasia mutated (ATM) function. It acetylates histone 4-lysine 16 (H4K16). The protein is a modulator of embryonic stem cells and an epigenetic regulator. It has been associated with gastric carcinoma.


Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.


Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles


技术参数 Specifications
biological sourcehuman
recombinantexpressed in baculovirus infected Sf9 cells
assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
mol wt ~83 kDa
NCBI accession no.BC037773
application(s)cell analysis
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... KAT8(84148)
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